Mplus code for mediation, moderation, and moderated mediation modelsModel 75: 1 or more mediators, in parallel if multiple (example uses 1), 2 moderators, both moderating both the IV- Mediator path and the Mediator-DV path Example Variables: 1 predictor X, 1 mediator M, 2 moderators W, Z, 1 outcome Y Preliminary notes: The code below assumes that
  Model Diagram: ![]()   Statistical Diagram: ![]()   Model Equation(s):
Y = b0 + b1M + b2W + b3Z + b4MW + b5MZ + c'X
 
Algebra to calculate indirect and/or conditional effects by writing model as Y = a + bX:
Y = b0 + b1M + b2W + b3Z + b4MW + b5MZ + c'X
Y = b0 + b1(a0 + a1X + a2W + a3Z + a4XW + a5XZ) + b2W + b3Z + b4(a0 + a1X + a2W + a3Z + a4XW + a5XZ)W + b5(a0 + a1X + a2W + a3Z + a4XW + a5XZ)Z + c'X
Y = b0 + a0b1 + a1b1X + a2b1W + a3b1Z + a4b1XW + a5b1XZ + b2W + b3Z + a0b4W + a1b4XW + a2b4WW + a3b4ZW + a4b4XWW + a5b4XZW + a0b5Z + a1b5XZ + a2b5WZ + a3b5ZZ + a4b5XWZ + a5b5XZZ + c'X
Y = (b0 + a0b1 + a2b1W + a3b1Z + b2W + b3Z + a0b4W + a2b4WW + a3b4ZW + a0b5Z + a2b5WZ + a3b5ZZ) + (a1b1 + a4b1W + a5b1Z + a1b4W + a4b4WW + a5b4ZW + a1b5Z + a4b5WZ + a5b5ZZ + c')X
One indirect effect(s) of X on Y, conditional on W, Z:
a1b1 + a4b1W + a5b1Z + a1b4W + a4b4WW + a5b4ZW + a1b5Z + a4b5WZ + a5b5ZZ = (a1 + a4W + a5Z)(b1 + b4W + b5Z)
One direct effect of X on Y:
c'
 
Mplus code for the model:
! Predictor variable - X
USEVARIABLES = X M W Z Y XW XZ MW MZ;
! Create interaction terms
DEFINE:
ANALYSIS:
! In model statement name each path and intercept using parentheses
MODEL:
   Y ON X(cdash);
   [M] (a0);
! Use model constraint subcommand to test conditional indirect effects
! 2 moderators, 3 values for each, gives 9 combinations
MODEL CONSTRAINT:
    LOW_W = #LOWW;   ! replace #LOWW in the code with your chosen low value of W
    LOW_Z = #LOWZ;   ! replace #LOWZ in the code with your chosen low value of Z
! Calc conditional indirect effects for each combination of moderator values
    ILOW_LOZ = a1*b1 + a4*b1*LOW_W + a5*b1*LOW_Z + a1*b4*LOW_W +     ILOW_MEZ = a1*b1 + a4*b1*LOW_W + a5*b1*MED_Z + a1*b4*LOW_W +     ILOW_HIZ = a1*b1 + a4*b1*LOW_W + a5*b1*HIGH_Z + a1*b4*LOW_W + ! Calc conditional total effects for each combination of moderator values
    TLOW_LOZ = ILOW_LOZ + cdash;
    TLOW_MEZ = ILOW_MEZ + cdash;
    TLOW_HIZ = ILOW_HIZ + cdash;
! Use loop plot to plot conditional indirect effect of X on Y for each combination of low, med, high moderator values
    PLOT(PLOW_LOZ PMEW_LOZ PHIW_LOZ PLOW_MEZ PMEW_MEZ PHIW_MEZ     LOOP(XVAL,1,5,0.1);
    PLOW_LOZ = ILOW_LOZ*XVAL;     PLOW_MEZ = ILOW_MEZ*XVAL;     PLOW_HIZ = ILOW_HIZ*XVAL; PLOT:
OUTPUT:
 
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