Mplus code for mediation, moderation, and moderated mediation modelsModel 67: 1 or more mediators, in parallel if multiple (example uses 1), 2 moderators, both moderating both the Mediator-DV path and the direct IV-DV path, 1 of which also moderates the IV-Mediator path Example Variables: 1 predictor X, 1 mediator M, 2 moderators W, V, 1 outcome Y Preliminary notes: The code below assumes that
  Model Diagram: ![]()   Statistical Diagram: ![]()   Model Equation(s):
Y = b0 + b1M + b2MW + b3MV + c1'X + c2'W + c3'XW + c4'V + c5'XV
 
Algebra to calculate indirect and/or conditional effects by writing model as Y = a + bX:
Y = b0 + b1M + b2MW + b3MV + c1'X + c2'W + c3'XW + c4'V + c5'XV
Y = b0 + b1(a0 + a1X + a2W + a3XW) + b2(a0 + a1X + a2W + a3XW)W + b3(a0 + a1X + a2W + a3XW)V + c1'X + c2'W + c3'XW + c4'V + c5'XV
Y = b0 + a0b1 + a1b1X + a2b1W + a3b1XW + a0b2W + a1b2XW + a2b2WW + a3b2XWW + a0b3V + a1b3XV + a2b3WV + a3b3XWV + c1'X + c2'W + c3'XW + c4'V + c5'XV
Y = (b0 + a0b1 + a2b1W + a0b2W + a2b2WW + a0b3V + a2b3WV + c2'W + c4'V) + (a1b1 + a3b1W + a1b2W + a3b2WW + a1b3V + a3b3WV + c1' + c3'W + c5'V)X
One indirect effect(s) of X on Y, conditional on W, V:
a1b1 + a3b1W + a1b2W + a3b2WW + a1b3V + a3b3WV = (a1 + a3W)(b1 + b2W + b3V)
One direct effect of X on Y, conditional on W, V:
c1' + c3'W + c5'V
 
Mplus code for the model:
! Predictor variable - X
USEVARIABLES = X M W V Y XW XV MW MV;
! Create interaction terms
DEFINE:
ANALYSIS:
! In model statement name each path and intercept using parentheses
MODEL:
   Y ON X(cdash1);
   [M] (a0);
! Use model constraint subcommand to test conditional indirect effects
! 2 moderators, 3 values for each, gives 9 combinations
MODEL CONSTRAINT:
    LOW_W = #LOWW;   ! replace #LOWW in the code with your chosen low value of W
    LOW_V = #LOWV;   ! replace #LOWV in the code with your chosen low value of V
! Calc conditional indirect effects for each combination of moderator values
    ILOW_LOV = a1*b1 + a3*b1*LOW_W + a1*b2*LOW_W + a3*b2*LOW_W*LOW_W +     ILOW_MEV = a1*b1 + a3*b1*LOW_W + a1*b2*LOW_W + a3*b2*LOW_W*LOW_W +     ILOW_HIV = a1*b1 + a3*b1*LOW_W + a1*b2*LOW_W + a3*b2*LOW_W*LOW_W + ! Calc conditional direct effects for each combination of moderator values
    DLOW_LOV = cdash1 + cdash3*LOW_W + cdash5*LOW_V;
    DLOW_MEV = cdash1 + cdash3*LOW_W + cdash5*MED_V;
    DLOW_HIV = cdash1 + cdash3*LOW_W + cdash5*HIGH_V;
! Calc conditional total effects for each combination of moderator values
    TLOW_LOV = ILOW_LOV + DLOW_LOV;
    TLOW_MEV = ILOW_MEV + DLOW_MEV;
    TLOW_HIV = ILOW_HIV + DLOW_HIV;
! Use loop plot to plot conditional indirect effect of X on Y for each combination of low, med, high moderator values
    PLOT(PLOW_LOV PMEW_LOV PHIW_LOV PLOW_MEV PMEW_MEV PHIW_MEV     LOOP(XVAL,1,5,0.1);
    PLOW_LOV = ILOW_LOV*XVAL;     PLOW_MEV = ILOW_MEV*XVAL;     PLOW_HIV = ILOW_HIV*XVAL; PLOT:
OUTPUT:
 
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