Mplus code for mediation, moderation, and moderated mediation modelsModel 64: 1 or more mediators, in parallel if multiple (example uses 1), 2 moderators, both moderating both the Mediator-DV path, 1 of which also moderates the IV-Mediator path Example Variables: 1 predictor X, 1 mediator M, 2 moderators W, V, 1 outcome Y Preliminary notes: The code below assumes that
  Model Diagram: ![]()   Statistical Diagram: ![]()   Model Equation(s):
Y = b0 + b1M + b2W + b3V + b4MW + b5MV + c'X
 
Algebra to calculate indirect and/or conditional effects by writing model as Y = a + bX:
Y = b0 + b1M + b2W + b3V + b4MW + b5MV + c'X
Y = b0 + b1(a0 + a1X + a2W + a3XW) + b2W + b3V + b4(a0 + a1X + a2W + a3XW)W + b5(a0 + a1X + a2W + a3XW)V + c'X
Y = b0 + a0b1 + a1b1X + a2b1W + a3b1XW + b2W + b3V + a0b4W + a1b4XW + a2b4WW + a3b4XWW + a0b5V + a1b5XV + a2b5WV + a3b5XWV + c'X
Y = (b0 + a0b1 + a2b1W + b2W + b3V + a0b4W + a2b4WW + a0b5V + a2b5WV) + (a1b1 + a3b1W + a1b4W + a3b4WW + a1b5V + a3b5WV + c')X
One indirect effect(s) of X on Y, conditional on W, V:
a1b1 + a3b1W + a1b4W + a3b4WW + a1b5V + a3b5WV = (a1 + a3W)(b1 + b4W + b5V)
One direct effect of X on Y:
c'
 
Mplus code for the model:
! Predictor variable - X
USEVARIABLES = X M W V Y XW MW MV;
! Create interaction terms
DEFINE:
ANALYSIS:
! In model statement name each path and intercept using parentheses
MODEL:
   Y ON X (cdash);
   [M] (a0);
! Use model constraint subcommand to test conditional indirect effects
! 2 moderators, 3 values for each, gives 9 combinations
MODEL CONSTRAINT:
    LOW_W = #LOWW;   ! replace #LOWW in the code with your chosen low value of W
    LOW_V = #LOWV;   ! replace #LOWV in the code with your chosen low value of V
! Calc conditional indirect effects for each combination of moderator values
    ILOW_LOV = a1*b1 + a3*b1*LOW_W + a1*b4*LOW_W + a3*b4*LOW_W*LOW_W +     ILOW_MEV = a1*b1 + a3*b1*LOW_W + a1*b4*LOW_W + a3*b4*LOW_W*LOW_W +     ILOW_HIV = a1*b1 + a3*b1*LOW_W + a1*b4*LOW_W + a3*b4*LOW_W*LOW_W + ! Calc conditional total effects for each combination of moderator values
    TLOW_LOV = ILOW_LOV + cdash;
    TLOW_MEV = ILOW_MEV + cdash;
    TLOW_HIV = ILOW_HIV + cdash;
! Use loop plot to plot conditional indirect effect of X on Y for each combination of low, med, high moderator values
    PLOT(PLOW_LOV PMEW_LOV PHIW_LOV PLOW_MEV PMEW_MEV PHIW_MEV     LOOP(XVAL,1,5,0.1);
    PLOW_LOV = ILOW_LOV*XVAL;     PLOW_MEV = ILOW_MEV*XVAL;     PLOW_HIV = ILOW_HIV*XVAL; PLOT:
OUTPUT:
 
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